If you want the best buzz from your morning cup of java, wait until you have been awake at least one hour to drink it. Why the delay? By doing so, you’re consuming caffeine at just the right time for it to work best with your body’s hormones, giving you an optimal level of alertness. It’s all about working with our Circadian rhythms — instead of fighting them. The Circadian rhythms are also known as your biological clock, that internal mechanism that wakes you up and makes you sleepy, among other things. To wake you up in the morning, your biological clock governs the release of cortisol, which is also called the stress hormone and is linked to our level of alertness. AsapScience reports that you are most likely to produce cortisol the first hour you are awake. If you drink coffee while your cortisol is naturally ramping up, it diminishes the natural effect of the caffeine and actually causes you to build up a greater tolerance to it — so much so that you will need ever greater amounts of caffeine for the same impact. But when you wait to drink coffee until you have been awake and out of bed for at least one hour and your body’s cortisol surge has ended, you’ll get the maximum bang from the caffeine. Other times to drink coffee to be in sync with your biological clock are between noon and 1pm and 5:30pm to 6:30pm.